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How long does it take Atorvastatin to work? Atorvastatin is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in your blood. Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the The International Network of Cholesterol Skeptic Here are the facts! Click on the blue arrows if you want the scientific evidence! Atorvastatin is generally well tolerated and side effects are usually mild. In studies, the most common side effects associated with Atorvastatin were constipation, flatulence, indigestion, and abdominal pain. If you are prescribed Atorvastatin, your healthcare professional may want to conduct routine blood tests to check your liver function before and after starting treatment. Be sure to tell your healthcare professional if you have any allergies to food or medication. Also, report promptly any unexplained muscle pain, tenderness, or weakness, particularly if accompanied by discomfort or fever, as these symptoms may be signs of serious side effects. For information about taking Atorvastatin along with other medicines, see your doctor or pharmacist. If you experience side effects, be sure to tell your doctor or other healthcare professional. Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. Atorvastatin is a very effective medicine for lowering high LDL cholesterol—the main target of cholesterol-lowering therapy. Your doctor will determine how much your LDL cholesterol needs to be lowered, based on your overall risk of heart disease. Atorvastatin also effectively lowers high blood-triglyceride levels. What is Atorvastatin?