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Some people should not take Atorvastatin. Those with active liver disease or possible liver problems; women who are pregnant, could possibly become pregnant, or are breast-feeding; and people who are allergic to any of the ingredients in LIPITOR. Atorvastatin is a prescription drug in one of the newest classes of cholesterol-lowering medications, called statins. These drugs have been used widely for the last five years. For people with high cholesterol, Atorvastatin, in combination with a low-fat diet, can reduce your LDL cholesterol and triglyceride levels. How does Atorvastatin work? Who should not take Atorvastatin tablets? There is no evidence that too much animal fat and cholesterol in the diet promotes atherosclerosis or heart attacks. For instance, more than twenty studies have shown that people who have had a heart attack haven't eaten more fat of any kind than other people, and degree of atherosclerosis at autopsy is unrelated with the diet. The following Information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. The only effective way to lower cholesterol is with drugs, but neither heart mortality or total mortality have been improved with drugs the effect of which is cholesterol-lowering only. On the contrary, these drugs are dangerous to your health and may shorten your life. Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture. Keep this and all medications out of the reach of children. How long does it take Atorvastatin to work? Generally, Atorvastatin works within 2 weeks. The full effect is usually seen within 4 weeks and lasts as long as you continue taking it. Always take Atorvastatin as directed by your healthcare professional. New cholesterol guidelines for converting healthy people into patients Atorvastatin is generally well tolerated and side effects are usually mild. In studies, the most common side effects associated with Atorvastatin were constipation, flatulence, indigestion, and abdominal pain. If you are prescribed Atorvastatin, your healthcare professional may want to conduct routine blood tests to check your liver function before and after starting treatment. Be sure to tell your healthcare professional if you have any allergies to food or medication. Also, report promptly any unexplained muscle pain, tenderness, or weakness, particularly if accompanied by discomfort or fever, as these symptoms may be signs of serious side effects. Most people will require the starting dose, which is a 10 mg tablet once daily. Your doctor will prescribe the dose that is right for you, which may be 10 mg to 80 mg. Atorvastatin can be taken any time of the day, with or without food. To make it easier to remember to take Atorvastatin you can plan to take it at the same time each day, such as after you brush your teeth in the evening. The amount or how often Atorvastatin is taken should never be changed without consulting your healthcare professional. Atorvastatin is a very effective medicine for lowering high LDL cholesterol—the main target of cholesterol-lowering therapy. Your doctor will determine how much your LDL cholesterol needs to be lowered, based on your overall risk of heart disease. Atorvastatin also effectively lowers high blood-triglyceride levels. How long does it take Atorvastatin to work? In medical studies of people with high cholesterol, Atorvastatin, taken once a day, had the following effects at doses of 10 to 80 mg: Lowered total cholesterol by 29-45%. Lowered LDL cholesterol, the "bad" cholesterol, by 39-60%. Increased HDL cholesterol, the "good" cholesterol, by 5-9%. Lowered triglyceride levels by 19-37%.