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Atorvastatin is a prescription drug in one of the newest classes of cholesterol-lowering medications, called statins. These drugs have been used widely for the last five years. For people with high cholesterol, Atorvastatin, in combination with a low-fat diet, can reduce your LDL cholesterol and triglyceride levels. How does Atorvastatin work? For information about taking Atorvastatin along with other medicines, see your doctor or pharmacist. If you experience side effects, be sure to tell your doctor or other healthcare professional. Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture. Keep this and all medications out of the reach of children. How does Atorvastatin improve the different types of cholesterol? The new cholesterol-lowering drugs, the statins, do prevent cardio-vascular disease, but this is due to other mechanisms than cholesterol-lowering. Unfortunately, they also stimulate cancer in rodents. In medical studies of people with high cholesterol, Atorvastatin, taken once a day, had the following effects at doses of 10 to 80 mg: Lowered total cholesterol by 29-45%. Lowered LDL cholesterol, the "bad" cholesterol, by 39-60%. Increased HDL cholesterol, the "good" cholesterol, by 5-9%. Lowered triglyceride levels by 19-37%. Some people should not take Atorvastatin. Those with active liver disease or possible liver problems; women who are pregnant, could possibly become pregnant, or are breast-feeding; and people who are allergic to any of the ingredients in LIPITOR. What would I need to know about taking Atorvastatin? Generally, Atorvastatin works within 2 weeks. The full effect is usually seen within 4 weeks and lasts as long as you continue taking it. Always take Atorvastatin as directed by your healthcare professional.